's Target Organ Toxicity in Marine and Freshwater Teleosts: PDF

ISBN-10: 0203361407

ISBN-13: 9780203361405


Addressing the varied gaps in present info, aim Organ Toxicology in Marine and Freshwater Teleosts is a necessary source for researchers and execs in aquatic toxicology and environmental hazard overview. all of the chapters are written by means of researchers who're across the world known for his or her paintings in mechanistic facets of aquatic toxicology. each one bankruptcy makes a speciality of a particular objective organ or physiological procedure and describes how a variety of brokers disrupt the conventional physiological process and strategies. This quantity is dedicated to express organs with insurance of the gill, kidney, epidermis, liver and intestine. The better half quantity, structures, offers assurance of poisonous results within the valuable apprehensive, immune, neurobehavioural and reproductive structures in addition to describing basic mechanisms of toxicity.

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Extra resources for Target Organ Toxicity in Marine and Freshwater Teleosts: Organs

Example text

General responses to toxicants General structural responses Mallatt (1985) has provided a comprehensive and quantitative synthesis of more than 100 toxicologic studies in which structural changes in the gills were examined by light or electron microscopy. This heroic review produced a number of important conclusions, which in general were supported by both earlier (Eller, 1975) and later (Evans, 1987; Lauren, 1991; Laurent and Perry, 1991; Wendelaar Bonga and Lock, 1992; McDonald and Wood, 1993; Heath, 1995; Wendelaar Bonga, 1997) reviews, that remain valid today.

Low pH Environmental acidity is one of the most thoroughly studied toxicants, reflecting the acid rain problem which drove research in the 1970s and 1980s. This phenomenon is relevant only in freshwater, most usually poorly buffered softwaters, although acid mine drainage may contaminate harder waters. In nature (and probably unwittingly in some laboratory exposures), responses are often complicated by the simultaneous presence of metals, particularly aluminum, mobilized at low pH. 0, in the absence of aluminum, respiratory effects are negligible, although ventilation does tend to increase.

This interpretation is in accord with the fact that these lesions are reported more commonly during chronic exposures than during acutely lethal exposures. , 1994b) and mucous cell proliferation by the ionoregulatory hormone prolactin, which is mobilized in freshwater fish in response to low plasma electrolyte levels. Indeed, there is considerable circumstantial evidence (summarized by Wendelaar Bonga, 1997) that the whole cell cycle of mitosis, maturation, senescence, and death is accelerated during sublethal toxicant exposure.

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Target Organ Toxicity in Marine and Freshwater Teleosts: Organs

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